Renoprotection with and without blood pressure reduction
نویسندگان
چکیده
منابع مشابه
Renoprotection: a matter of blood pressure reduction or agent-characteristics?
Data from recent clinical trials show that lowering of BP reduces the rate of renal function loss in chronic renal disease. There is evidence supporting the assertion that BP lowering obtained by intervention in the renin-angiotensin-aldosterone system (RAAS) has an additive renoprotective effect in both diabetic and nondiabetic renal diseases. However, to dissociate BP-dependent and non-BP-dep...
متن کاملRole of aliskiren in blood pressure control and renoprotection
Patients with chronic renal disease are at increased risk for the development of cardiovascular disease, which is the main cause of death in this growing population. Among the risk factors involved, hypertension and proteinuria are major contributors to kidney damage and, if not controlled, may eventually lead to the progression of renal failure and end-stage renal disease. Both proteinuria and...
متن کاملRenoprotection, renin inhibition, and blood pressure control: the impact of aliskiren on integrated blood pressure control
Hypertension (HTN) is an important factor in progressive loss of renal function. The kidney can be both a contributor to and a target of HTN. The functional integrity of the kidney is vital for the maintenance of cardiovascular homeostasis. Chronic activation of the renin system causes HTN and, ultimately, end-organ damage. Direct renin inhibitors (DRIs) inhibit plasma renin activity (PRA), the...
متن کاملTo compare the efficacy of blood pressure reduction with or without the biochemical profile
Background Resistant hypertension (RH) is common among adults with hypertension affecting up to 30% of patients on treatment for blood pressure (BP) control. It is predicted to increase, as old age and obesity are considered major risk factors for RH. Effective treatment of RH still remains an unmet goal of antihypertensive treatment. This thesis compared two methods of treating RH in two hospi...
متن کاملBlood Pressure Reduction and Secondary Stroke Prevention
Structured summary2 Provide a structured summary including, as applicable: background; objectives; data sources; study eligibilitycriteria, participants, and interventions; study appraisal and synthesis methods; results; limitations; conclusionsand implications of key findings; systematic review registration number.p.4(manuscript)
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ژورنال
عنوان ژورنال: Kidney International
سال: 2005
ISSN: 0085-2538
DOI: 10.1111/j.1523-1755.2005.09414.x